Role of mRNA expression of interleukin-6 and interleukin-10 in idiopathic preterm birth
نویسندگان
چکیده
Background: India is one of the nation’s leading in number preterm births (PTB), as reported by WHO. Despite extensive research exact cause PTB remains elusive. The present study was designed to effect inflammatory genes (proinflammatory IL-6 and anti-inflammatory IL-10) etiopathogenesis idiopathic PTB.Methods: Maternal blood placental tissue samples cases (n=263) equal term delivery controls were collected at time delivery. mRNA expression IL-10 gene analysed using Real-time PCR.Results: (pro-inflammatory) 11.73 folds high maternal 2.60 higher compared birth cases. (anti-inflammatory) 25 lower 10 deliveries.Conclusions: Interleukins have been identified a major role birth.
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ژورنال
عنوان ژورنال: International journal of reproduction, contraception, obstetrics and gynecology
سال: 2022
ISSN: ['2320-1770', '2320-1789']
DOI: https://doi.org/10.18203/2320-1770.ijrcog20222310